Studies with large cohort of patients
are available
From 1995
to 1999, 559 patients were included in a European multi-centric
study (1). Most of the patients (n=402) were T1-T2 patients
treated with Ablatherm-HIFU as first choice therapy. In this
T1-T2 population, negative biopsies were observed in 87.2%
of the patients. At least 50% of the patients presented a
nadir PSA at 0.1 or less after a complete treatment.
A special highlight on the biopsy results according to the disease
related initial risk level shows that 92,1 % of the low risk patients
(cancer involving less than half a lobe, PSA <10ng/ml and Gleason
sum lower or equal to 6) presented negative biopsies during their
overall follow-up (up to 51 months).
(1) C. Chaussy, S. Thüroff, G. Vallancien,
W. Wieland, H.J. Kiel, A. Le Duc, F. Desgranchamps, J. de la Rosette,
A. Gelet - HIFU for the Treatment of Localized Prostate Cancer:
Efficacy Results of the European Multicentric Study - The Journal
Of Urology, May 2001, Vol. 165, 5:388